INTERMITTENT CLAUDICATION AND PROGNOSIS OF ATHEROSCLEROTIC LESIONS OF LOWER LIMB ARTERIES: RESULTS OF PROSPECTIVE STUDY

A.L. Komarov, E.P. Panchenko, A.D. Deev, K.K. Davletov, A.P. Eshkeeva, L.A. Markova, Yu.A. Karpov

Results of prospective study of 123 patients with atherosclerotic lesions in lower limb arteries are presented. Morbidity, mortality, clinical course of intermittent claudication and dynamics of atherosclerotic manifestation (ischemic heart disease, cerebral ischemia) were analyzed throughout 3-5-year follow-up period (mean period – 4.2 years).

Patients with atherosclerotic lesions in lower limb arteries and intermittent claudication were characterized by high rate of cardiovascular risk factors and disseminated atherosclerotic process with involvement of aorta, coronary and cerebral arteries. Mortality rate among patients included into the study was 26% in the follow-up period, thrombotic complications occurred in 26% of patients, half being fatal. Dynamic observations showed that walking distance remained unchanged or increased, occurrence of ischemic heart disease raised from 44% to 72%, of cerebral ischemia – from 13% to 28%.

KEY WORDS: atherosclerotic lesions of lower limb arteries, ischemic heart disease, cerebral ischemic disease.

P. 9-18

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