Journal «Angiology and Vascular Surgery» • 

2001 • VOLUME 7 • №3

SULODEXIDE IN COMBINED THERAPY OF SEVERE DIABETIC FOOT SYNDROME

V.V. Mikhalsky, S.V. Goriunov, I.A. Sementsova, I.A. Butivschenko, Yu.P. Atanov, D.V. Romashov
Department of Suppurative Surgery Urban Clinical Hospital №15,
Moscow Department of Hospital Surgery №1, Russian State Medical University,
Moscow, Russia

Outcomes of 58 patients with various forms of diabetic foot treated by Sulodexide in complex therapy are presented. Effectiveness of treatment and microcirculatory changes were assessed by laser Doppler flowmetry. The use of Sulodexide in combination with radical surgical management of suppurative focus allowed to reduce the rate of amputations from 29.2% in control to 6.9% in test group, as well as to accelerate the onset of the second phase of wound healing process (on 5.7±0.8 days) and to achieve foot reconstruction in 27.1% of patients.

KEY WORDS: diabetic foot syndrome, Sulodexide.

P. 33-36

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