INTRAOPERATIVE ADMINISTRATION OF LOW-MOLECULAR-WEIGHT HEPARINS IN RECONSTRUCTIVE VASCULAR OPERATIONS

Pokrovsky A.V., Demidova V.S., Titova M.L, Gontarenko V. N., Burtseva E.A.
Department of Vascular Surgery State Federal Facility "A.V. Vishnevsky Institute of Surgery under the Russian Medical Technologies",
Moscow, Russia

The article deals with analysing the outcomes of administering low-molecular-weight heparins (LMWH) by the example of nadroparin ("Fraxiparin") during the intraoperative period in patients diagnosed with atherosclerotic lesions of femoropoplietal-crural segment of the lower-limb arteries as compared with non-fractionated heparin (NFH). Studied were the alterations in the parameters of the plasmatic and thrombocytic links of haemostasis on the background of administering various molecular-weight fractions of heparin. A conclusion was drawn on advantageous use of LMWH in the cohort of the patients involved. Also presented herein is an analysis of the literature data concerning appropriate usage of LMWH during the intraoperative period.

KEY WORDS: reconstructive vascular operations, thrombosis, low-molecular-weight heparin, non-fractionated heparin.

P. 17-20

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