Journal «Angiology and Vascular Surgery» • 

2010 • VOLUME 16 • №3

CLINICAL AND MORPHOLOGICAL PARALLELS OF VARIOUS DEGREES OF CHRONIC ARTERIAL INSUFFICIENCY OF LOWER LIMBS

Kuznetsov M.R., Chernikov V.P., Teplyakov S.A., Sizarev A.V., Tougdumov В.V., Gabieva M.G., Dzhalilova N.S.
Chair of Faculty Surgeiy of the Moscow Department of the Russian State Medical University Scientific Research Institute of Human Morphology under the Russian Academy of Medical Sciences,
Moscow, Russia

The article deals with the main clinical and instrumental methods of determining severity of chronic arterial insufficiency of the lower extremities, showing possibilities of morphological studies for an accurate diagnosis of the ischaemia degree. Also determined are promising trends of studying the hypoxia-inducible factor (HIF) and vascular endothelial growth factor (VEGF) in assessment of ischaemic impairments of lower-extremities tissue.

KEY WORDS: chronic arterial insufficiency of lower-limbs, vascular endothelial growth factor (VEGF), hypoxia-inducible factor (HIF), diagnosis.

P. 152-157

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