Journal «Angiology and Vascular Surgery» • 

2010 • VOLUME 16 • №4

POSSIBILITIES OF RADIONUCLIDE STUDY OF LOWER-LIMB MUSCLES PERFUSION IN DIAGNOSIS OF CHRONIC ARTERIAL INSUFFICIENCY

Karalkin A.V.1, Kuznetsov M.R.2, Teplyakov S.A.2, Tugdumov В.V.2, Rumyantseva E.I.2
1 – Chair of Faculty Surgery of the Russian State Medical University,
2 – Chair of Faculty Surgery of the Moscow Faculty of the Russian State Medical University,
Moscow, Russia

The authors have hereby proposed a method to diagnose lower-limb muscular ischaemia by means of scintigraphy, used in 35 patients suffering from atherosclerosis obliterans with stage IIB and III A chronic arterial insufficiency of limbs.

To do so, administration of the radioactive agent «Myoview» (99mTc-tetrophosmine) manufactured by the «Nycomed» Company into a patient's peripheral vein was followed by assessing its accumulation in lower-limb muscles at rest and after standard physical load. Alterations in the parameters studied relative to the norm made it possible to judge on the presence of lower-limb circulatory impairments.

The method proved highly efficient, thus making it possible to use it for both therapeutic decision-making and probably in future for dynamic control after the treatment performed. Minimally invasive nature and simplicity in use of the methodology open wide possibilities for its use.

KEY WORDS: radionuclide study, muscular ischaemia, atherosclerosis obliterans, chronic arterial insufficiency of limbs.

P. 47-51

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