Journal «Angiology and Vascular Surgery» • 

2015 • VOLUME 21 • №4

Sulodexide in conservative treatment of peripheral arterial diseases

Kuznetsov M.R.1, Kosykh I.V.2, Tolstikhin V.Yu.3, Kuznetsova V.F.1, Magnitsky L.A.1

1) Department of Faculty Surgery No1 of the Therapeutic Faculty of the Russian National Research Medical University named after N.I. Pirogov,
2) Department of Faculty Surgery No2 of the Therapeutic Faculty of the Russian National Research Medical University named after N.I. Pirogov, Moscow, Russia
3) Department of Surgical Diseases, Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Krasnoyarsk, Russia

Presented in the article is a review of the literature, analysing principles of conservative therapy of patients with obliterating diseases of lower limb arteries and most commonly used drugs to treat them, followed by discussing the mechanisms of action and efficacy of such pharmacological agents as pentoxyphyllin, cilostazol, naphthidrofuryl, aktovegin, sulodexide. Described in details are subtle mechanisms of action of sulodexide as an endothelioprotector, its clinical efficacy in intermittent claudication.

KEY WORDS: atherosclerosis, peripheral arterial diseases, chronic arterial insufficiency, intermittent claudication, pentoxyphyllin, cilostazol, naphthidrofuryl, aktovegin, sulodexide.

P. 51

« Back

Angiologia.ru - portal for professionals
VLAANT
Lancet
HI-TECHNOLOGY MEDICINE