HAEMORHEOLOGICAL PROBLEMS IN LOWER-LIMB CHRONIC ARTERIAL INSUFFICIENCY

Petukhov E.B., Kuznetsov M.R., Fedin A.I., Virganskii А.О., Kuznetsova V.F., Komov K.V., Teplyakov S.A., Kholopova E.A., Sizarev A.V., Lisenkov O.P., Ibraguimov T.M.
Chair of Faculty Surgery of the Moscow Department,
Chair of Neurology of the Advanced Medical Training Department of the Federal Educational Facility of the Higher Vocational Education Russian State Medical University under the Russian Public Health Ministry,
Moscow, Russia

The article deals with the findings obtained in examining and treating a total of eighty-seven patients suffering from atherosclerosis obliterans of the lower-limb arteries with stage ПВ and HI chronic arterial insufficiency. Studied were impairments of the rheological properties of the blood and plasma, erythrocytic deformability and the concentration of malonic dialdehyde in blood at admission to the hospital, upon completion of the course of conservative treatment, and after the reconstructive vascular intervention performed. It was determined that the leading mechanism disturbing oxygen utilization by tissues is a decrease in erythrocytic deformability, which promotes shunting of the arterial blood flow and persists after the surgical vascular reconstruction preformed.

KEY WORDS: atherosclerosis obliterans, lower-limb chronic arterial insufficiency, haemorheological properties, reconstructive vascular operations, functional capabilities of the vessels of the microcirculatory bed.

The work was carried out under financial support provided by the Russian Foundation for Fundamental Research, grants: 07-01-00734, 07-07-00380, 08-01-12029, 08-07-00354.

P. 13-18

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