Journal «Angiology and Vascular Surgery» • 

2013 • VOLUME 19 • №2

Lymphatic endothelium in certain pathological conditions

Nimaev V.V.1, Lyubarsky M.S.1, Shevela A.I.2

1) Scientific Research Institute of Clinical and Experimental Lymphology under the Siberian Branch of the Russian Academy of Medical Sciences
2) Institute of Clinical Biology and Fundamental Medicine under the Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia

Presented herein is a review of the literature data concerning the structural and functional peculiarities of the endothelium of the lymphatic and blood vessels. The authors consider the current state of the art of the problem regarding dysfunction of lymphatic endothelium dysfunctions developing in various diseases, as well as in the process of ontogenesis, pointing out an important role of impaired processes of lymphangiogenesis, underlying the development of diseases of the lymphatic system. The authors also assess administration of quercetine in treatment for chronic venous insufficiency, followed by suggesting a possible mechanism of its positive action consisting in a decrease in the oedema at early stages of lymphoedema.

KEY WORDS: endothelium, lymphatic, lymphoedema, quercetin.

P. 38

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