Journal «Angiology and Vascular Surgery» • 

2014 • VOLUME 20 • №1

Immunological aspects of formation of restenoses after endothelial lesions

Kozyreva V.S., Subbotovskaya A.N., Shilova A.N., Karpenko A.A.

Novosibirsk Scientific Research Institute for Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public health, Novosibirsk, Russia

The article deals with an analysis of the literature data concerning immunological mechanisms of the formation of restenoses after damage of the arterial wall, considering the participants of the early and late phases of inflammatory response initiated by endothelial damage. Also given is characteristics of the process of formation on the neointima, followed by description of the role of intercellular adhesion molecules in initiation and maintaining of the processes of acute and chronic inflammation.

KEY WORDS: restenosis, precursors of endothelial cells, intercellular adhesion molecules.

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