Journal «Angiology and Vascular Surgery» • 

2010 • VOLUME 16 • №4

ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH LOWER-LIMB VARICOSE DISEASE AND POSSIBILITIES OF CORRECTION THEREOF

Shevchenko Yu.L., Stoiko Yu.M., Gudymovich V.G., Nikitina A.M., Trifonov S.I.
State Federal Facility «National Medical Surgical Centre named after N.I. Pirogov under the Ministry of Health and Social Development of the Russian Federation»,
Moscow, Russia

Endothelium as the main structural unit of the vessel appears to exert a considerable influence on the processes of regulation of the cardiovascular system. The authors generalize herein and present the findings of the studies aimed at investigating endothelial dysfunction in varicose disease. Based on analysing the results of various methods of study they show importance of endothelial dysfunction, followed by discussing possibilities of medicamentous correction thereof, proceeding from pathogenetic mechanisms of its development.

KEY WORDS: endothelial dysfunction, chronic venous insufficiency, varicose disease, endothelioprotectors.

P. 99-104

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