Lymphotropic therapy in patients after surgical revascularization of lower-limb vessels

Charyshkin A.L.¹, Yashkov M.V.^1,2, Gumerov I.I.^1,2, Maxin A.A.^1,2

1) Department of Vascular Surgery, Institute of Medicine, Ecology and Physical Culture, Ulyanovsk State University,
2) Department of Thoracic Surgery, Ulyanovsk Regional Hospital, Ulyanovsk, Russia

Occlusive and stenotic lesions of lower-limb arteries appear to be amongst the most common manifestations of the pathology of the cardiovascular system and are characterized by various degree of chronic arterial insufficiency. Revascularization is the main stage of treatment for chronic arterial insufficiency of the lower extremities. Performing a reconstructive operation aimed at restoring the arterial blood flow in the ischaemized extremity is accompanied and followed by the development of reperfusion syndrome.

The purpose of this study was to assess efficacy of using regional lymphotropic therapy for treatment of reperfusion syndrome in patients with chronic ischaemia of lower limbs in the postoperative period.

The study included two groups of patients: the comparison group with standard postoperative treatment and the study group where the standard therapy was supplemented with regional lymphotropic therapy.

In the postoperative period, the patients in both groups developed reperfusion oedema of the operated lower limb on day 3 after arterial reconstruction, however, on POD 7 after revascularization, the severity of oedema was apparently less in the study group. Lymphorrhoea after operative treatment in the study group was encountered significantly less often as compared with the control group. According to the findings of ultrasonographic examination of soft tissues in the postoperative period, patients of both groups on POD 3 were found to have pronounced oedema of soft tissues. However, on POD 7 the study group patients demonstrated a dramatic decrease in the thickness of oedema of the subcutaneous fat versus the comparison group patients.

Regional lymphotropic therapy after reconstructive operations on arteries of lower limbs promoted a decrease in the severity of reperfusion syndrome on the operated lower limb.

KEY WORDS: reperfusion syndrome, obliterating atherosclerosis of lower-limb arteries, chronic ischaemia of lower limbs, reconstructive vascular surgery, lymphotropic therapy.

P. 141

« Back