Journal «Angiology and Vascular Surgery» • 

2013 • VOLUME 19 • №1

Experience in using antistax® in patients with lower limb chronic venous insufficiency and accompanying arterial hypertension

Sabelnikov V.V.1, Sholkov S.I.2

1) North-Western State Medical University named after I.I. Mechnikov
2) Medical Centre Open Joint-Stock Company "Admiralty Shipyards", St. Petersburg, Russia

The main pathogenetic causes of the development of lower limb chronic venous insufficiency (CVI) are associated with hypertension in the inferior vena cava, venous stasis, and ischaemia of the vascular wall. Alterations in microcirculation responsible for the metabolic and trophic processes of the venous wall appear on the background of change in the macrocirculatory bed. A considerable role of the venous endothelial dysfunction was noted. Prescription of phleboprotectors and phlebotonics is of fundamental importance. Efficacy of Antistax makes it possible to recommend its use in combined therapy of various-aetiology and various-grade CVI.

KEY WORDS: lower limb chronic venous insufficiency, phleboprotectors, microcirculation, endothelial dysfunction, flavonoids.

P. 85

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